Selected publications


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Targeting the conserved stem loop 2 motif in the SARS-CoV-2 genome.


Valeria Lulla, Michal P Wandel, Katarzyna J Bandyra, Rachel Ulferts, Mary Wu, Tom Dendooven, Xiaofei Yang, Nicole Doyle, Stephanie Oerum, Rupert Beale, Sara M O'Rourke, Felix Randow, Helena J Maier, William Scott, Yiliang Ding, Andrew E Firth, Kotryna Bloznelyte, Ben F Luisi


Journal of Virology, vol. 95(14), 2021 Jun 1


A hidden gene in astroviruses encodes a viroporin


Valeria Lulla, Andrew E. Firth


Nature Communications, vol. 11(1), 2020 Jul 13, pp. 4070-4070


Enterovirus Competition Assay to Assess Replication Fitness.


Valeria Lulla, Andrew E. Firth


Bio-protocol, vol. 9(10), 2019 Apr 20


An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells


Valeria Lulla, Adam M. Dinan, Myra Hosmillo, Yasmin Chaudhry, Lee Sherry, Nerea Irigoyen, Komal M. Nayak, Nicola J. Stonehouse, Matthias Zilbauer, Ian Goodfellow, Andrew E. Firth


Nature microbiology, vol. 4(2), 2019 Jan 1, pp. 280-292


Mutation of CD2AP and SH3KBP1 binding motif in alphavirus nsP3 hypervariable domain results in attenuated virus


Margit Mutso, Ainhoa Moliner Morro, Cecilia Smedberg, Sergo Kasvandik, Muriel Aquilimeba, Mona Teppor, Liisi Tarve, Aleksei Lulla, Valeria Lulla, Sirle Saul, Bastian Thaa, Gerald M McInerney, Andres Merits, Margus Varjak


Viruses, vol. 10(5), 2018 Mar 27


Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge.


Valeria Lulla, Andres Losada, Sylvie Lecollinet, Adeline Kerviel, Thomas Lilin, Corinne Sailleau, Cecile Beck, Stephan Zientara, Polly Roy


Vaccine, vol. 35(33), 2017 Jun 24, pp. 4262-4269


Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes.


Valeria Lulla, Aleksei Lulla, Kerstin Wernike, Andrea Aebischer, Martin Beer, Polly Roy


Journal of Virology, vol. 90(16), 2016 May 8, pp. 7405-7414


Mutations Conferring a Noncytotoxic Phenotype on Chikungunya Virus Replicons Compromise Enzymatic Properties of Nonstructural Protein 2


Age Utt, Pratyush Kumar Das, Margus Varjak, Valeria Lulla, Aleksei Lulla, Andres Merits


Journal of Virology, vol. 89(6), 2015 Feb 15, pp. 3145-3162


Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response


Zhisheng Her, Zhisheng Her, Terk-Shin Teng, Jeslin J L Tan, Teck-Hui Teo, Teck-Hui Teo, Yiu-Wing Kam, Fok-Moon Lum, Fok-Moon Lum, Wendy W L Lee, Wendy W L Lee, Christelle Gabriel, Rossella Melchiotti, Rossella Melchiotti, Anand K Andiappan, Valeria Lulla, Aleksei Lulla, Mar K Win, Angela Chow, Subhra K Biswas, Yee-Sin Leo, Marc Lecuit, Andres Merits, Laurent Rénia, Lisa F P Ng, Lisa F P Ng, Lisa F P Ng


Embo Molecular Medicine, vol. 7(1), 2015 1, pp. 24-41


Prime-Boost Immunization Strategies against Chikungunya Virus


David Hallengärd, Fok-Moon Lum, Beate M. Kümmerer, Aleksei Lulla, Valeria Lulla, Juan García-Arriaza, John K. Fazakerley, Pierre Roques, Roger Le Grand, Andres Merits, Lisa F. P. Ng, Mariano Esteban, Peter Liljeström


Journal of Virology, vol. 88(22), 2014 Oct 15, pp. 13333-13343


Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.


David Hallengärd, Maria Kakoulidou, Aleksei Lulla, Beate M. Kümmerer, Daniel X. Johansson, Margit Mutso, Valeria Lulla, John K. Fazakerley, Pierre Roques, Roger Le Grand, Andres Merits, Peter Liljeström


Journal of Virology, vol. 88(5), 2014 Feb 1, pp. 2858-2866


Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis


Valeria Lulla, Liis Karo-Astover, Kai Rausalu, Andres Merits, Aleksei Lulla


Journal of Virology, vol. 87(18), 2013 Aug 15, pp. 10207-10220


RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication.


Andrei Nikonov, Tarmo Mölder, Rein Sikut, Kaja Kiiver, Andres Männik, Urve Toots, Aleksei Lulla, Valeria Lulla, Age Utt, Andres Merits, Mart Ustav, Mart Ustav


PLOS Pathogens, vol. 9(9), 2013 Aug 5


Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout


Sabine Gläsker, Aleksei Lulla, Valeria Lulla, Therese Couderc, Therese Couderc, Jan Felix Drexler, Peter Liljeström, Marc Lecuit, Marc Lecuit, Marc Lecuit, Christian Drosten, Andres Merits, Beate Mareike Kümmerer


Virology Journal, vol. 10(1), 2013 Jun 15, pp. 235-235


A Pathogenic Role for CD4+ T Cells during Chikungunya Virus Infection in Mice


Teck-Hui Teo, Teck-Hui Teo, Fok-Moon Lum, Fok-Moon Lum, Carla Claser, Valeria Lulla, Aleksei Lulla, Andres Merits, Laurent Rénia, Lisa F. P. Ng, Lisa F. P. Ng


Journal of Immunology, vol. 190(1), 2013 1, pp. 259-269


Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus


Nele Tamberg, Valeria Lulla, Rennos Fragkoudis, Aleksei Lulla, John K Fazakerley, Andres Merits, Andres Merits


Journal of General Virology, vol. 88(4), 2007 Mar 1, pp. 1225-1230